Wu Lei participated in Zegna's 2025 Chinese New Year campaign, showcasing the Year of the Snake collection. The campaign featured designs with snake motifs, including the Il Conte jacket and Triple Stitch sneakers.

Wu Lei was appointed as Burberry's global brand ambassador in July 2025. He has participated in various campaigns, including the 2025 Qixi Festival campaign featuring a seaside meeting and the Chinese New Year campaigns for the 2025 Year of the Snake collection. As one of China’s influential young stars, Wu has captivated audiences, solidifying his rising status in film and television.