Bradley Cooper became the brand ambassador for IWC Schaffhausen in April 2018, featuring in a global advertising campaign showcasing the Big Pilot’s Watch Edition 'Le Petit Prince'. This campaign marked the first extensive on and offline initiative for the Swiss luxury watch manufacturer with a single ambassador, highlighting IWC's appeal to adventurous individuals.

Bradley Cooper was appointed as the global ambassador for BOSS Fragrances in 2025, joining Maluma and Vinicius Júnior in the campaign for BOSS Bottled Beyond Eau de Parfum, which emphasizes themes of brotherhood and mutual inspiration.

Bradley Cooper was appointed as the brand ambassador for Louis Vuitton in 2023, making his debut with the Tambour Twenty campaign directed by Damien Chazelle, which highlights the 20th anniversary of the Tambour watch collection.

Bradley Cooper partnered with Talenti Gelato & Sorbetto in 2024 for the 'Raise the Jar' campaign. This campaign highlights Talenti's unique slow cooking process and authentic recipes, celebrating the brand's connection to traditional preparation methods, like those of a real Argentinian grandma for its dulce de leche.